X-Ray Crystallography Is A Widely Used Technique In Physics, Chemistry, Biology, And Other Sciences. To Use This Technique, Researchers Crystallize A Material (Usually A Protein, Mineral, Or Some Other Type Of Molecule) And Then Bombards It With X-Rays, Producing Diffraction Patterns That Can Be Used To Investigate The Crystal's Physical Properties. This Information Allows Scientists To Determine The Atomic Structure Of The Crystallized Material, And In Turn Helps Them Understand Its Behavior And Properties. When Scientists Irradiate Crystallized Materials With X-Rays, The Rays Scatter In Different Directions Based On The Size And Placement Of The Crystals. From This Data, Scientists Are Able To Determine The Size And Shape Of The Crystallized Material’s Molecules, As Well As Secure Information About Its Composition And Properties. Knowing The Crystal’s Shape, Researchers Can Discover How Its Chemical Bonds Are Arranged, And Which Atoms Are Bound To One Another. To Determine The Exact Structure Of A Crystallized Material, Scientists Must Calculate Its Precise ‘Form Factor’ - An Equation That Shows How X-Rays React To Each Atom In The Crystal. With This, And Other Calculations, Scientists Can Determine The Electron Density Of The Material, Which Reveals Its Exact Structure. In Recent Years, The Use Of X-Ray Crystallography Has Led To Many Fascinating Discoveries About The Chemical And Physical Properties Of A Wide Array Of Materials. For Instance, Researchers Have Determined The Structures Of Various Viruses, Which Can Help Them Find Ways To Fight Different Illnesses. Additionally, Scientists Have Applied X-Ray Crystallography To Engineer New Materials, Such As More Heat- And Pressure-Resistant Plastic Components For Jet Engines, And Medications That Use Fewer Synthetic Ingredients And Thus Have Fewer Side Effects. In The Near Future, Many More Discoveries Are Certain To Come From X-Ray Crystallography.
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Kyeongjae Cho, University of Texas at Dallas, United States
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Alexander Bagaturyants, Retired, Israel
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Stanislaw Dzwigaj, Sorbonne Université, France
Title : Distal functionalization via transition metal catalysis
Haibo Ge, Texas Tech University, United States