Accurate biochemical analysis is fundamental to diagnosing, monitoring, and managing diseases, making clinical chemistry essential in modern healthcare. Advanced techniques such as spectrophotometry, chromatography, and immunoassays enable precise measurement of biomarkers, enzymes, hormones, and metabolites in bodily fluids. The development of point-of-care diagnostics and high-throughput automated analyzers enhances the speed and accuracy of medical testing. Personalized medicine relies on biochemical profiling to tailor treatments based on an individual’s metabolic and genetic makeup. Innovations in biosensors and lab-on-a-chip technologies are revolutionizing real-time health monitoring and early disease detection. With the integration of artificial intelligence and big data, clinical chemistry continues to improve diagnostic precision, paving the way for more effective therapeutic strategies and better patient outcomes in a rapidly evolving medical landscape.