Medicinal Chemistry and Drug Discovery

Medicinal chemistry is the science of creating and synthesizing molecules with the goal of improving them and turning them into new drugs for treating diseases. It's an interdisciplinary field with roots in organic chemistry, biology, and pharmacology, among other areas. The chemical subject of medicinal chemistry, sometimes known as pharmaceutical chemistry, is concerned with the design, development, and synthesis of pharmaceutical medications. To identify, develop, and synthesise chemical agents with a therapeutic purpose, as well as to analyse the qualities of existing medications, the discipline integrates skills from chemistry and pharmacology.

Drug discovery is the process of discovering novel candidate pharmaceuticals in the domains of medicine, biotechnology, and pharmacology. Modern drug discovery entails identifying screening hits, medicinal chemistry, and optimization of those hits to improve affinity, selectivity (to lower the risk of side effects), efficacy/potency, metabolic stability (to extend the half-life), and oral bioavailability. The drug development process can resume after a molecule that meets all of these criteria has been identified. Clinical trials are developed if the experiment is successful.