Drug Discovery Is The Process By Which New Medications Are Designed And Identified For Commercial Utilization. Drug Discovery Is An Important And Lengthy Process That Involves Drug Design And Research, Target Identification, Target Validation, Lead Generation, Lead Optimization, Pharmacology, Toxicology, Pre-Clinical Trial Testing, Clinical Trials, Drug Approval, And Commercialization. The Initial Stages Of Drug Discovery Involve Drug Design And Research, Wherein A Wide Variety Of Chemical Molecules Are Synthesized And Tested. Computational Approaches Are Widely Used To Design And Modify Molecules That Match Specific Targets. The Information From This Research Is Then Used To Identify Biologically Relevant Targets That Could Be Influenced With A Drug Treatment. Once A Target Has Been Identified, The Process Moves To Target Validation. Here, Further Validation Techniques Are Utilized To Assess The Biological Relevance And The Clinical Potential Of That Target. Lead Generation And Lead Optimization Is The Next Step Of The Process. Through The Testing Of Tens Of Thousands Of Low-Potency Compounds, Molecules With Potential Therapeutic Effects Are Identified And Optimized To Enhance Bioavailability And Overall Potency. Pharmacology And Toxicology Are Then Used To Evaluate The Safety, Efficacy, And Side Effects Of The Identified Compounds In Pre-Clinical Trials. The Successful Outcomes Of These Pre-Clinical Studies Can Then Be Moved To Clinical Trials. Here, The Effects Of The New Drug Are Tested On Individuals To Further Assess Its Efficacy And Safety. If These Trials Prove Successful, The Drug Can Then Be Filed For Approval, After Which It Is Introduced Into The Market. Overall, Drug Discovery Is A Complex But Necessary Process For The Development Of New And Commercialized Drugs. Through The Progressive Stages Of Drug Design, Target Identification, Lead Generation, And Clinical Trials, Many New Medications Are Developed And Released Yearly.
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Kyeongjae Cho, University of Texas at Dallas, United States
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Yong Xiao Wang, Albany Medical College, United States
Title : Nanostructured biodevices based on carbon nanotubes and glyconanoparticles for bioelectrocatalytic applications
Serge Cosnier, Silesian University of Technology, Poland
Title : Chemical engineering of vanadium, titanium or chromium zeolites for application in environmental catalysis
Stanislaw Dzwigaj, Sorbonne Université, France
Title : Distal functionalization via transition metal catalysis
Haibo Ge, Texas Tech University, United States
Title : Advances in plasma-based waste treatment for sustainable communities
Hossam A Gabbar, Ontario Tech University, Canada