Clinical Trials Are Conducted To Prove The Safety And Effectiveness Of New Drugs Or Medical Treatments. Synthesis Of Clinical Trials Is The Process Of Consolidating Multiple Clinical Trials Into One Systematic Review. This Technique Is Used By Researchers To Draw Out Valid Data When Many Trials Are Conducted To Investigate A Single Outcome. Synthesis Of Clinical Trials Helps Researchers To Determine Whether A Drug Or Treatment Works And Is Safe For Use. The Methodology Used Depends On The Type Of Clinical Trial Being Synthesised, With Qualitative Studies Using Narrative Reviews And Meta-Analysis Used To Identify And Combine The Results Of Quantitative Studies. Depending On The Scope Of The Trial, There Could Be Anywhere From A Few Studies To Dozens That Need To Be Incorporated Into The Analysis. To Begin The Synthesis Process, Researchers Must First Obtain The Raw Data From The Trials. For Quantitative Studies, This Will Involve Collecting Data On Study Design, Characteristics, Results And Outcomes, Among Other Factors. Narrative Reviews Use Narrative Text From The Original Published Papers. Meta-Analysis Syntheses Use The Standardized Mean Differences And Effect Sizes To Combine Data From The Trials. Once The Data Is Collected, Researchers Then Begin The Analysis Of The Data. For Quantitative Studies, This Involves The Assessment Of Bias And The Calculation Of The Appropriate Statistical Method For The Data. Narrative Reviews Typically Involve A Comprehensive Review Of The Trial’s Results And Outcomes. Meta-Analysis Syntheses Are More Complex And Involve Systematic Reviews, Meta-Analysis Methods, And Heterogeneity Testing. Synthesis Of Clinical Trials Is An Important Process That Helps Researchers To Draw Useful Data From Multiple Studies. This Process Helps To Ensure That Drugs And Treatments Are Effective And Safe For Use.
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