HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

4th Edition of

Chemistry World Conference

June 17-19, 2024 | Paris, France

Chemistry 2024

Deepak Wadhwa

Speaker at Chemistry World Conference 2024 - Deepak Wadhwa
Chaudhary Bansi Lal University, India
Title : Unveiling thioredoxin inhibitor potential: Synthesis and characterization of thiazole compounds


Thioredoxin reductase (TrxR) is an enzyme that contains selenocysteine and is in charge of preserving redox equilibrium in cells. Despite having uses in other therapeutic areas such neurodegeneration, inflammation, microbial infections, and neonatal hyperoxic lung injury, TrxR has primarily been seen as a target for anticancer drugs. Moreover, from synthetic point of view, transition metal free, multicomponent approach is attracting utmost attention world-wide in modern organic chemistry. Hence, greener methodology is adopted for the synthesis of biologically important thiazole molecules. C-5 sulfenylated thiazoles are synthesized using thiophenols as Sulphur source and thiazoles in Iodine/DMSO at 90 ? [scheme1]. Excellent yields are obtained with easy workup methodology. Synthesized compounds were characterized via NMR, Mass spectroscopy and IR spectroscopy. Further, synthesized compounds were evaluated as thioredoxin reductase inhibitor and alpha amylase inhibitor.
Key words- thiazole, thiophenol, thiolation, iodine, DMSO, Thioredoxin inhibitor, alpha amylase inhibitor.

Audience Take Away:

  • The audience from the presentation or discussion on "Unveiling Thioredoxin Inhibitor Potential: Synthesis and Characterization of Thiazole Compounds" can expect to learn several key points:
    • Thioredoxin Inhibitors significance in various fields, such as medicine and biology
    • Thiazole Compounds structure and properties
    • Biological Applications of thiazole compounds can be applied in the context of thioredoxin inhibition. This may involve insights into potential medical or therapeutic applications
    • Chemical Techniques and methods used in the synthesis and characterization of these compounds. This might include insights into laboratory procedures and analytical tools

      Overall, the presentation on this topic aims to provide a comprehensive understanding of the synthesis and characterization of thiazole compounds and their potential as thioredoxin inhibitors, offering valuable knowledge to researchers, scientists, and professionals interested in this field.

  • The presentation will likely touch on the broader implications of this research, including its potential impact on various scientific fields and its relevance to current research trends. Therefore, faculty could use to expand their research or teaching
  • The audience might gain insights into potential future directions in this area of study, including ongoing research and potential applications in drug development or other industries


Dr. Deepak Wadhwa studied Chemistry at the Kurukshetra University, Kurukshetra and graduated in 2000. He then joined the research group of Prof. Om Parkash Arora & Prof. Jitender Kumar Sharma at the Department of Chemistry, Kurukshetra University, Kurukshetra. he received his Ph.D. degree in 2012 at the same institution. After that he obtained the position of an Assistant Professor at the Chaudhary Bansi Lal University, Bhiwani. He has published more than 20 research articles in SCI(E) journals.