Title : Selective and sustainable catalysis for transforming C-H bonds
Abstract:
The development of green approaches to access new functional molecules has been impacting and improving the quality of lives. Processes with the best possible step and atom economy have been a preeminent goal of synthetic chemistry. Seeking new reactivity and selectivity in catalysis provides enormous opportunities for the construction of molecular complexity. Research in our laboratory focuses on developing next-generation inorganic and organometallic catalysts, and their applications in synthetic and medicinal chemistry. We are particularly interested in organometallic and mechanistic study-guided development of new patterns of selectivities for bond activation, bond formation, and tandem catalysis. Among ongoing directions, our group has been developing ruthenium(II)-catalyzed C?H functionalization processes as mechanistically unique and operationally practical tools for the stereoselective functionalization of various sites of arenes and alkenes. With the specific directions, we aim to gain new understandings and enrich selective and sustainable access to new molecules that have close relevance to bioactive compounds, chiral organic materials, synthetic building blocks, and future ligand toolboxes for catalysis.
Audience Take-Away:
- The audience will learn about recent development in sustainable methods for converting C-H bonds to functional molecules.
- The practical, energy and material-saving design of the catalytic processes would encourage industry applications for drug molecule synthesis.
- The application of co-catalysis for this development in controlling the stereoselectivity and reactivity for C-H functionalization would inspire the design of new green synthesis with minimum energy consumption and waste generation.
