Title : Recent advances of magnetic gold hybrids and nanocomposites, and their potential biological applications
Magnetic gold nanoparticles (mGNP) have become a great interest of research for nanomaterial scientists because of their significant magnetic and plasmonic properties applicable in biomedical applications. Various synthetic approaches and surface modification techniques have been used for mGNP including the most common being the coprecipitation, thermal decomposition, and microemulsion methods in addition to the Brust Schiffrin technique, which involves the reduction of metal precursors in a two-phase system (water and toluene) in the presence of alkanethiol. The hybrid magnetic–plasmonic nanoparticles based on iron core and gold shell are being considered as potential theragnostic agents. Herein, in addition to future works, we will discuss recent developments for synthesis and surface modification of mGNP with their applications in modern biomedical science such as drug and gene delivery, bioimaging, biosensing, and neuro-regenerative disorders. I shall also discuss the techniques based on my research related to the biological applications of mGNP.
Keywords: Nanohybrids; magnetic gold nanoparticles; nanocomposites; surface functionalization; core-shell nanocomposites; magnetic-plasmonic nanoparticles; biological applications