Title : Phytochemical study and biological activities of organic extracts flower heads, leaves, and roots of rhaponticumacaule L.(DC) from northwestern algeria
Abstract:
Rhaponticum acaule L. (DC) called “Tafgha” is a wild medicinal plant belonging to the flora of the region of Tlemcen. The chemical composition of its capitula is interesting, given the presence of polyunsaturated fatty acids with values between 32.5% and 52.7%. Proteins have an average percentage in capitula (11.37%) with a remarkable composition of essential amino acids. The highest content of total polyphenols (135.31mg EAG/g) was reported in leaf extracts and flavonoids (0.24mg CEQ/g) in capitula extracts... The effect of capitula extract on cell proliferation of the two lines 4T1 and AMB-231 showed a reduction in breast cancer cell proliferation in a dose-dependent manner, with an IC50 ranging from 13.33µg/ml to 11.61µg/ml.
