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5th Edition of

Chemistry World Conference

June 02-04, 2025 | Rome, Italy

Chemistry 2024

Phytochemical analysis, antifungal and antibacterial screening of artocarpus altilis: Guyana flora extracts

Speaker at Chemistry World Conference 2024 - Brij Bushan Tewari
University of Guyana, Guyana
Title : Phytochemical analysis, antifungal and antibacterial screening of artocarpus altilis: Guyana flora extracts

Abstract:

The plant material leaves of Artocarpus altilis (Breadfruit) were collected from university of Guyana road, Cummings lodge, Guyana.  Leaves are dried in oven at 50-55 ºC for 72 h.  The moisture content is calculated. The dried leaves were grounded and extracted in each acetone, ethanol and   methanol solvents.  Extracts were collected and evaporation of solvent was done on rotavapour.  The respective solvent was added to viscous semi solid liquid extract to make up the desired volume of extract solution. The antimicrobial and antifungal activity of both plants were examined by well diffusion method, poison plate method, paper disc plate method and streak plate methods. In Artocarpus altilis leaves extract studies, maximum and minimum antimicrobial potential was observed for methanol and acetone solvent extracts, respectively. All plant extracts showed   antimicrobial potential toward the organisms Staphylococcus aureus, Escherichia coli and Candida albicans. The phytochemical analysis of methanol leaves extract of breadfruit tested positive for flavonoids, terpinoids, phenol, phlobatannins , steroids and phytosteroids and negative for tannins , saponins , alkaloids and cardiac glycosides . It is observed from the present studies that leaves extract of Artocarpus altilis have antimicrobial property and its potential increases as their amount increases. Medical benefits of breadfruit extracts include, cardiovascular health, good for skin, reduce diabetes, dental health, energy booster, bone health, sleep better at night, resistance against infection etc. The wood of breadfruits one of the most valuable timbers in the construction of traditional houses. Breadfruit contains phytochemicals having potential as an insect repellent. Present research work is very useful for the researchers of similar research interest.

Audience Take Away:

  • Accuracy of result can be improved by accurate measurement of inhibitory zone
  • Triplicate experiment
  • Phytochemical screening can be done by two methods
  • Studies on medical potential of local medicinal plants can be attempted
  • Crude green drugs can be prepared and tested
  • Further studies on   more phytochemicals can be attempted

Biography:

Brij Bhushan Tewari is a Professor of Chemistry in the Department of Chemistry at University of Guyana. Prof. Tewari obtained the Doctor of Philosophy degree in Science (Chemistry) 1985 from Allahabad University, India.  He has taken teaching/research appointments at several universities in Asia, Europe, USA, Canada and Guyana. His major research interests are in the area of (i) Metal complexes in biology and medicine (ii) Astrobiology & chemical evolution and origins of life (iii) Environment, Microbiology and Agriculture. He has published 133 research papers in international journal, one book and seven book chapters.

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