HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

4th Edition of

Chemistry World Conference

June 17-19, 2024 | Paris, France

Chemistry 2023

Habiba Amira Guebailia

Speaker at Chemistry World Conference 2023 - Habiba Amira Guebailia
Laboratory of Applied Chemistry -LCA, University, Algeria
Title : Donor-acceptor interaction between biologically active hesperetin 7-rhamnoglucoside and ?-acceptors DDQ and TCNE


The interactions between a biologically active flavonoid, Hesperetin 7-rhamnoglucoside ( HESP) and two of the most known π- acceptors DDQ and TCNE were investigated leading to two new charge transfer complexes (CTC). UV- Visible spectrophotometry was used to follow the reactions in solution in methanol and ethanol as sol- vents. Infrared and NMR spectrophotometry was used to characterize the products formed in the solid state reactions. The1:1 stoichiometry of formed charge transfer complexes (HESP-DDQ and HESP-TCNE) was con- firmed by Molar ratio method and Benesi-Hildbrand equation was used to calculate the formation constants K CT and the molar extinction coefficient ? CT of the formed CTC. CTC formed in the reaction of Hesperetin 7-rhamnoglucoside with π-acceptors DDQ and TCNE showed high formation constants K CT.  K CT values for both CTC formed in ethanol are higher than those formed in methanol and those found for the HESP-DDQ CTC were higher than those of HESP-TCNE. Our results suggest the formation of stable CT complexes of Hesperetin 7-O-rhamnoglucoside with π-acceptors DDQ and TCNE which could enhance biological properties of this phytochemical and accelerates its use a full-fledged medicine.

Audience Take Away:

  • Improvement of bioavailability of plant metabolites through charge transfer complexation
  • Use of plant polyphenols as full-fledged medicines



Dr. Amira-Guebailia studied Chemistry at the Guelma University, Algeria and graduated as Chemical engineer  in 1991 and got a Magister degree in 1994.  She then joined the research group of Prof. Jean-Michel Mérillon at Bordeaux II University in France and she received her PhD degree in 2007 at Guelma University, Algeria in collaboration with Bordeaux II University in France. She obtained the position of an Associate Professor, lecturer then professor of chemistry at Guelma University. She has published more than 14 research articles in SCI(E) journals and supervised 7 PhD theses.