HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.

4th Edition of

Chemistry World Conference

June 17-19, 2024 | Paris, France

Chemistry 2023

Eva Falomir Ventura

Speaker at Chemistry World Conference 2023 - Eva Falomir Ventura
Jaume I University, Spain
Title : Aryl triazole-scaffold for multitarget anticancer immunomodulating drug discovery


A small library of aryl triazole-scaffold derivatives have been developed using click chemistry synthetic strategies. Docking studies using PD-L1 and VEGFR-2 crystallographic data confirmed their potential targeted action. The antiproliferative activity on monocultures of several tumour cell lines (HT-29, A-549 and MCF-7), and on the non-tumour cell line HEK-293 has been studied. Also, the effect on anticancer targets (PD-L1, VEGFR-2 and c-Myc) has been evaluated. Finally, the effect on cancer cell viability when co-cultured with immune cells (Jurkat T cells or THP-1) has been also studied together with their effect on IL-6 secretion to cell media.

Audience Takeaway Notes:

  • The audience will learn more about multitarget anticancer drug discovery for oncoimmunomodulating therapies.
  • Those people in the audience involved in Drug Discovery research could use most of the information we are going to provide.
  • This is a multidisciplinary and interdisciplinary work so people from research fields involved in Medicinal Chemistry, Biochemistry, Organic Chemistry, Cell biology, Immunology could be interested.


Dr. Eva Falomir studied Chemistry at the Valencia University, Spain and graduated as MS in 1994. She then joined the research group of Prof. Carda at Jaume I University (UJI). She received her PhD degree in 1998 at the same institution. After two years postdoctoral fellowship supervised by Dr A. Fürstner at Max-Planck Institute, Germany she obtained the position of an Associate Professor at UJI. In 2022, she got a Full Professor position in the same university. She has published more than 100 research articles in SCI(E) journals.