Title : ZnO nanoparticles native collagen films with electro conductive properties
Abstract:
Background: Valorization of industrial wastes has brought a special interest in terms of environmental sustainability. In this context, agro-industrial wastes, such as skin residues from bovine leather tanning industry, have become a collagen source within green strategy.
Objective: Incorporation of ZnO nanoparticles (NPs) into collagen formulations to prepare films and investigate their effect on film properties.
Methods: Collagen was obtained from bovine skin by mechanical treatments. Then, collagen, glycerol, and different amounts of ZnO NPs were mixed in acetic acid solution and films were prepared by solution casting. Finally, physicochemical (FTIR spectroscopy, mass loss, moisture content, swelling), thermal (DSC, DMA), barrier (UV-vis spectroscopy, WVP), morphological (XRD, SEM), mechanical, and electrical properties of the films were analyzed.
Results: Native collagen triple helix structure was maintained, as observed by FTIR and XRD analyses. Additionally, the obtained films showed induced electro-conductive properties, good mechanical performance and their physical integrity was maintained after immersion into PBS. Furthermore, films showed good occlusivity values for absorption of fluids.
Conclusion: ZnO NPs-collagen films could be used to promote cell growth and make these films suitable for biomedical applications, highlighting their potential use as wound dressings
Audience take away:
Revalorization of skin residues from tanning industry
? New procedures to obtain native collagen
? New procedure to obtain biofilms based on native collagen and its characterization.
? Electro-conductive properties of collagen if the native fibrous structure of collagen is maintained
